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JAMES BOTTESCH, MS
jbottesch@hboi.edu
Research Specialist
Division of Biomedical Marine Research (DBMR)
Harbor Branch Oceanographic Institution
J. Bottesch joined DBMR's Invertebrate Cell Culture group earlier this year. His work
currently entails methodologies for cryo-preservation and culturing cell lines from
Axinella corrugata, Xestospongia muta, and Niphates erecta. He is particularly
interested in determining the effects of exogenous perturbation upon the cell cycle of A.
corrugata and X. muta and delineating genes which seem to be upregulated or downregulated
as a result. Previous work with PiPets, LLC entailed the production of novel, transgenic
ornamental fish in terms of coloration, pattern formation, growth, and fertility,
utilizing Danio rerio as a model. In his graduate work, he studied the effects of a
teratogen, tributyltin chloride, on early piscine embryogenesis. His educational
background includes a pair of BS's from East Stroudsburg University of Pennsylvania and
an MS from the Florida Institute of Technology.

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